Sunday, October 25, 2020
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Liquor Monitoring – Who’s Controlling Your Liquor Costs?

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Liquor monitoring and control means different things to different people. If you’re the owner of a bar or a restaurant with a bar, the cost of your liquid assets is always on your mind. There is a lot more to it than your pour cost. Who is taking the physical inventory of your liquid assets? How often are physical inventories being taken? Who is verifying the individual item counts and costs? How are you controlling these liquid assets? If costs are high then what? Bartender pour testing, secret shoppers or more inventories?

If you are not monitoring verified pour costs you are pouring profits down the drain! If you are relying on your staff to control your liquid assets without verified controls you are pouring profits down the drain! If your pour cost is low enough and you are making plenty of profit you are a fortunate individual and this information is not for you.

We all know that a system that measures every pour and only dispenses drinks that have been recorded will drastically reduce most bar’s pour costs. You also know that a measured pour dispensing system is not going to work with your customers unless you are a hotel bar, casino bar, an airport bar or a cruise ship! Customers and your bartenders both want a free pour system with lots of over pouring and plenty of free drinks with as little management control as possible!

Seems like everyone is against the owner’s profit making efforts, so what options are available?

It all starts with inventory monitoring so you know what your real pour costs are. This means at least a weekly inventory of all liquid assets with verified counts and costs. Can your management staff do this? Maybe, depends on their compensation program and who is verifying their counts. You or your accountant should verify the item costs and inventory extensions, without accurate inventories of all beer, liquor and wine you are just wasting everyone’s time.

While you are working on accurate inventory data what about sales reporting? If you are still using a cash register to record sales into a few departments you will not be able to pinpoint and correct your inventory issues. Sure the bartenders don’t want to ring up drinks by brand, too slow they say! The real reason is too much control for their liking. As the owner, you can’t afford not to have this sales data. The high margin good old days are long gone. If all your bar sales are not being properly recorded how can you have an accurate pour cost? You can use free pour spouts and still control your liquid assets with individual bartender accountability!

The first option is to do it yourself with proper inventory controls, accurate costs and bartender accountability. There are several good programs out there that can help you set up the controls: Accubar, Bevintel or Scannabar just to name a few.

Want independent inventory counting, costing and reporting? Contact Bevintel for their complete program.

Want free pour and liquor control? Use wireless spouts that integrate with the POS system for complete control down to the individual bartender. Contact Bar Vision, Capton, Free Pour or Liquor Monitor for their solutions.

Want to lock down the bar completely with a hardware based control system? Contact Berg or Easy Bar.

Don’t forget to lock down your draft beer and wine by the glass. Most of the companies mentioned have systems for the rest of your liquid assets that also need to be controlled.



Source by Bob Frazier

Backbone Fever

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Dengue fever is transmitted by mosquitoes, Aedes aegypti, that usually occur in the tropics. It is caused by 4 related virus serotypes of flavivirus. Backbone fever is another name for dengue fever because it can extremely cause pain. Mosquitoes usually bite at dawn and dusk but can also bite anytime especially in dark areas, indoors and during cloudy and rainy weather.

Incubation of dengue fever ranges from five to fifteen days before signs appear on the infected person. It usually starts with fever, headache, swollen glands, joint pains and rash. There is rapid increase in body temperature and low heart rate. Other signs can also be pain behind the eyes. Sign of dengue fever lasts up to four days and is followed by sudden drop of temperature and sweating. There will be a day or two of normal body temperature then a second rise in body temperature followed by pinkish rash on the skin with bleeding gums and red soles and palms. Clinical test will show result of low platelet count.

For Dengue hemorrhagic fever (DHF), this is a severe case of dengue, will show higher body temperature and there can be bleeding of nose, ears, moth and blood may also ooze from the skin pores. It can also cause vascular leak syndrome in which fluids in the blood vessel leaks through the skin and goes into spaces around the belly and lungs. Blood pressure will fall due to fluid loss and can lead to Dengue shock syndrome (DSS). Dengue can affect other body organs that may lead to liver dysfunction, gastroenteritis, renal impairment and meningo-encephalitis.

Diagnosis of dengue is through clinical tests. Complete blood count will show low platelet count or called thrombocytopenia. Patients with dengue also show positive result in tourniquet test. There is also bruising, bloody diarrhea, vomiting, and bleeding. And plasma leakage is evident. In defining primary and secondary cases of dengue, Rapid Diagnostic test is used to avoid turning into life threatening fever.

Since dengue is caused by virus, there is no specific antibiotic to treat it. The treatments concern is to give patients relief from its symptoms. To prevent dehydration, supplementation of intravenous fluid and oral hydration therapy is recommended. It is critical to monitor vital signs too. Platelet transfusion may also arise depending on the severity of the disease. Rest is also required for patients to recover and regain strength for faster recover.

The use of no steroidal anti-inflammatory drugs and aspirin should only be taken if prescribed by doctor to avoid worsening hemorrhage. Patients can use paracetamol for joint and muscle pain. Dengue fever can be prevented by interrupting transmission of the virus. Patients can wear long sleeves and pants. Netting can also be used. Use of skin repellant is also advised. Try to limit exposure to mosquitoes by avoiding going out before sunset and after sunrise. Emptying stagnant water from trash cans, tin cans, flower pots and old tires can also help in removing places where mosquitoes live.

There is no vaccine available for dengue fever so it is best to be cautious and avoid areas where you can get it. Seek medical help if you think you have the said symptoms for correct diagnosis.



Source by Sunnez Madsen

ऋषि कपूर डेथ न्यूज़: अभिनेता ऋषि कपूर का 67 वर्ष की उम्र में निधन

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द्वारा: एंटरटेनमेंट डेस्क | नई दिल्ली |

अपडेट किया गया: 1 मई, 2020 8:09:36 सुबह

ऋषि कपूर मृत ऋषि कपूर 67 वर्ष के थे।

बॉलीवुड अभिनेता ऋषि कपूर लंबी लड़ाई के बाद गुरुवार को मुंबई में निधन हो गया कैंसर। वह 67 वर्ष के थे।

रणधीर कपूर ने ऋषि के निधन की खबर की पुष्टि की indianexpress.com। रणधीर ने कहा, “अभी उनका निधन हो गया।”

कपूर परिवार ने एक बयान में कहा, “हमारे प्रिय ऋषि कपूर का ल्यूकेमिया के साथ दो साल की लड़ाई के बाद आज सुबह 8:45 बजे अस्पताल में शांति से निधन हो गया। अस्पताल के डॉक्टरों और चिकित्सा कर्मचारियों ने कहा कि उन्होंने उन्हें अंतिम मनोरंजन दिया। वह जोवियल रहा और दो महाद्वीपों में दो साल के उपचार के माध्यम से पूरी तरह से जीने के लिए दृढ़ था। परिवार, दोस्त, भोजन और फिल्में उनका ध्यान बनी रहीं और इस दौरान उनसे मिलने वाला हर कोई इस बात से चकित था कि उन्होंने अपनी बीमारी को किस तरह से दूर नहीं होने दिया। वह अपने प्रशंसकों के प्यार के लिए आभारी थे जो दुनिया भर से आए थे। उसके गुजरने में, वे सभी समझेंगे कि वह एक मुस्कान के साथ याद किया जाना पसंद करेगा न कि आँसू के साथ। व्यक्तिगत नुकसान की इस घड़ी में, हम यह भी समझते हैं कि दुनिया बहुत कठिन और परेशान समय से गुजर रही है। आंदोलन और सार्वजनिक रूप से इकट्ठा होने के आसपास कई प्रतिबंध हैं। हम उनके सभी प्रशंसकों और शुभचिंतकों और परिवार के दोस्तों से अनुरोध करना चाहते हैं कि वे लागू होने वाले कानूनों का सम्मान करें। उसके पास कोई दूसरा रास्ता नहीं होगा। ”

30 अप्रैल को अंतिम सांस लेने से पहले, अभिनेता मुंबई के सर एचएन रिलायंस फाउंडेशन अस्पताल में एक सप्ताह के लिए आईसीयू सहायता पर थे।

ऋषि कपूर को 2018 में कैंसर का पता चला था और तब उन्होंने इलाज के लिए न्यूयॉर्क की यात्रा की थी। वह अपनी पत्नी, अभिनेता नीतू कपूर के साथ लगभग एक साल तक वहां रहे और सितंबर 2019 में मुंबई लौट आए।

ऋषि कपूर का करियरऋषि कपूर का करियर ऋषि कपूर को 2018 में कैंसर का पता चला था। (एक्सप्रेस आर्काइव फोटो)

भारत भर की हस्तियों ने शोक व्यक्त करने के लिए सोशल मीडिया का सहारा लिया।

अमिताभ बच्चन ट्विटर पर ले गया और लिखा, “टी 3517 – वह चला गया ..! ऋषि कपूर .. चले गए .. बस गुज़र गए .. मैं नष्ट हो गया हूँ! “

अक्षय कुमार ट्वीट किया, “ऐसा लगता है जैसे हम एक बुरे सपने के बीच में हैं … अभी-अभी #RishiKapoor जी के निधन की निराशाजनक खबर सुनी, यह दिल दहला देने वाला है।” वह एक किंवदंती, एक महान सह-कलाकार और परिवार का एक अच्छा दोस्त था। मेरे विचार और प्रार्थना उनके परिवार के साथ। ”

रजनीकांत ट्विटर पर पोस्ट किया गया, “दिल टूट गया … शांति में आराम करो … मेरे सबसे प्यारे दोस्त # ऋषि कपूर”

प्रियंका चोपड़ा ट्विटर पर साझा किया गया, “मेरा दिल बहुत भारी है। यह एक युग का अंत है। # शिशिर आपके स्पष्ट दिल और अथाह प्रतिभा का सामना फिर कभी नहीं करेगा। इस तरह के एक विशेषाधिकार के लिए आप भी थोड़ा सा जानते हैं। नीतू मैम, रिधिमा, रणबीर और परिवार के बाकी सदस्यों के प्रति मेरी संवेदना। शांति में रहिए सर। ”

ऋषि कपूर (1952-2020): एक सचित्र श्रद्धांजलि

“पौराणिक @chintskap सर के निधन की खबर से दिल टूट गया। फिल्में फिर कभी वैसी नहीं होंगी। शांति से आराम करें। प्रार्थनाएँ और दुआएँ परिवार और प्रशंसकों के लिए शक्ति की कामना करती हैं। # ऋषि कपूर, ”नुसरत जहान ने ट्विटर के माध्यम से कहा।

जूनियर एनटीआर ने ट्वीट किया, “दिल तोड़ने वाला !!! हमने सर्वोच्च प्रतिभाशाली को खो दिया इरफान खान साहब कल। और अब, महान ऋषि कपूर साब! यह भारतीय सिनेमा के लिए विनाशकारी नुकसान है। ”

यह भी पढ़ें | ऋषि कपूर: गायन-नृत्य-रोमांस नायक हम सभी को प्यार करना पसंद था | ऋषि कपूर का जन्म फिल्मों में हुआ था लेकिन उनका उपहार पूरी तरह से उनका खुद का था | सेलिब्रिटीज ने ऋषि कपूर के निधन पर शोक जताया | ऋषि कपूर पर 102 नॉट आउट के निर्देशक उमेश शुक्ला: वह वास्तव में जादू था | Per ऋषि कपूर एक हेलिकॉप्टर उड़ाना चाहते थे, लेकिन नासिर हुसैन ने उन्हें जाने नहीं दिया ’: वायु सेना अधिकारी ने याद किया | ऋषि कपूर ने अपने कैंसर के इलाज के बारे में सब कुछ बताया | ऋषि कपूर के 10 सर्वश्रेष्ठ गीत | ऋषि कपूर के बारे में आपको सब कुछ पता होना चाहिए | अभिलेखागार से – ऋषि कपूर: मुझे बॉबी में सबसे अच्छा ब्रेक मिला, लेकिन यह सब वहाँ से खिसक गया | ऋषि कपूर की दूसरी पारी की सर्वश्रेष्ठ फ़िल्में | आलिया भट्ट ने ऋषि कपूर को दी श्रद्धांजलि

ऋषि कपूर की फिल्मेंऋषि कपूर की फिल्में ऋषि कपूर 1970 से 1990 के दशक में एक लोकप्रिय अभिनेता थे। (एक्सप्रेस आर्काइव फोटो)

ऋषि कपूर दिग्गज अभिनेता के बेटे थे राज कपूर और कृष्णा कपूर उन्होंने श्री 420 में 3 साल की उम्र में फिल्मों में अपनी पहली उपस्थिति दर्ज की। उनकी पहली भूमिका राज कपूर निर्देशित मेरी नाम जोकर में थी। इसके बाद वह आरके फिल्म्स के बॉबी के साथ एक हार्टथ्रोब बन गए।

ऋषि कपूर 1970 से 1990 के दशक के दौरान एक लोकप्रिय अभिनेता थे जब उन्होंने अमर अकबर एंथोनी, कुली, कर्ज़ और चांदनी जैसी फिल्मों में काम किया। अपने बाद के वर्षों में, उन्हें हम तुम, अग्निपथ और कपूर एंड संस जैसी फिल्मों में अपने चरित्र भूमिकाओं के लिए जाना जाता था। उन्हें आखिरी बार द बॉडी के साथ देखा गया था इमरान हाशमी

ऋषि कपूर अपनी पत्नी नीतू कपूर और बच्चों से बचे हैं रणबीर कपूर और रिद्धिमा कपूर।

📣 इंडियन एक्सप्रेस अब टेलीग्राम पर है। क्लिक करें हमारे चैनल से जुड़ने के लिए यहां (@indianexpress) और नवीनतम सुर्खियों के साथ अपडेट रहें

सभी नवीनतम के लिए मनोरंजन समाचार, डाउनलोड इंडियन एक्सप्रेस ऐप।

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The Benefits Of Living In A Temperate Climate

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If you are looking for a new place to settle down and live, you have a number of options and considerations. Depending on where you are moving from, the weather may play a major role in your decision. If you have lived in an area of the country that battles storms or harsh winters, you may decide to move just to escape the stress of the environment. While weather does not have to be a big deal, when you are a homeowner, you end up worrying weather emergencies such as flooding, shoveling, and insulation. Over a period of time, this stress can wear you out and you may just decide to move somewhere where weather is less of a concern. If you are able to find employment in an area without weather concerns, you should make the move. CNA jobs and jobs in CNA are plentiful and provide a chance to live in a sunny, warm environment.

Living in a temperate environment will help improve your health. When the weather is comfortable, it makes you want to get outside and enjoy the outdoors. People are more likely to take up hobbies like hiking and jogging when the weather is comfortable all year-long. While activities like shoveling can be great workouts, it is not something you can count on doing several times a week. In an environment where the weather is moderate and predictable, you can commit to staying fit outdoors on the regular basis.

Making a life in a temperate climate will extend the life of your belongings. Your vehicle will not be exposed to bitter cold temperatures, road salt and other rust-causing elements. This means your car will last years longer in a warm climate than it would in a location with harsh winters. The weather will also have less of a bearing on your home. Time will be saved not having to winterize your home with insulation and you will not have to worry about snow removal from your sidewalks and outdoor areas.

If you live in an area that is warm year-round, you will have access to fresh foods all year-long. People who live in areas with harsh winters can visit the grocery store for fruits and vegetables, but they only have access to produce that has been shipped in from other areas. This means the food is not as fresh. If you live in a warm place, farmers can grow fresh fruits and vegetables all year-long. Residents of warm climates can visit farmers’ markets and get fresh produce any time of the year.

Finally, if you are thinking about moving to a less harsh climate, you should know your overall quality of life will improve. You can examine each of the pros and cons to moving, but in general, you are going to have more opportunities, more time for recreation and less weather-related stress if you live in an area where weather is not a concern. Regardless of the stress of moving, you will end up leading a healthier, happier life.



Source by Stewart Wrighter

Wine and Health Research – The Power of Procyanidins – The Real French Paradox

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Imagine that in future procyanidin pills are recommended just as aspirin is today. Such are the healthy properties of procyanidin, this is a possibility. Procyanidins have been identified as high performance, low toxicity and highly bio-available. Some red wines have been identified as containing extremely high concentrations of this powerful heart healthy compound.

A steady stream of animal and in vitro studies supplemented by epidemiological evidence and human studies reveal numerous health benefits. Chief among the benefits is antioxidant protection against heart disease and some cancers.

Consider these Imperatives

  • Procyanidins have been identified as high performance, low toxicity and highly bio-available.
  • Procyanidins, available in some red wines, 70% cocoa solids dark chocolate and other foods, is a healthy compound in the highest doses and part of a natural diet – NOT an unnaturally high-dose supplement (as with other compounds) that is not proven to be safe over the long term and possibly not even absorbed fully as has been observed with some supplements.
  • Research identifies that after two weeks of a daily glass of procyanidin rich red wine positive support for cardiovascular health was observed, including reduced blood pressure. This is good news for protection against heart disease and strokes.
  • The health statistics are significant and important — Almost half of us die of HEART DISEASE — World Health Organization, and 50% of STROKES are caused by high blood pressure.
  • Nowhere in the world where populations are given drug treatments to manage cardiovascular health, have they achieved the low levels of heart disease related deaths, as occurs in Gers (France) where they drink these wines” Professor Giovanni de Gaetano, M.D., Ph.D,
  • In south west France where they have make and consume wines high in procyanidins, census data shows there is twice the number of 90 year old males as the national average.
  • In this region the wines are up to 10 times more procyanidin rich than the modern style, sweet, soft, quaffing red wines so commonly made today.
  • In New Zealand, consumers who begin a strategy of a daily glass of the wines of south west France are experiencing blood pressure improvements consistent with the research. This occurs without change to lifestyle, diet, exercise or medication.
  • Procyanidins provide the same benefits, naturally, as would possibly be achieved with the “polypill”. The polypill is a mixture of already in use drugs that is intended to prevent heart attacks and strokes. Governments and drug companies internationally are trying to develop such a drug, to be taken daily, that is aimed to protect older populations from heart disease. In procyanidins it already exists in the natural form.
  • Perhaps there is significance for our health that with today’s prevalence of processed and refined foods, our consumption of procyanidins is much lower than the amount we likely evolved with!

This report is an illumination of the considerable international research that has been conducted into the health benefits of procyanidins.

What is Procyanidin

Procyanidins are a mixture of antioxidant molecules, variously called —

  • procyanidins
  • proanthocyanidins,
  • oligomeric procyanthocyanidins (OPC)
  • proanthocyanidolic oligomers (PCO)
  • leukocyanidins

Procyanidin, a polyphenol compound with strong bioactivity and pharmacologic activity, resides widely in grape seeds, hawthorn, pine bark and other foods and plants. A number of potential mechanisms of procyanidin have emerged. These include, serving as an important in vivo antioxidant, decreasing blood pressure, reducing risk of cancer, inhibiting bacteria, and so on. In recent years, the beneficial health and longevity effects of procyanidin on the human body has been extensively researched internationally.

Research has reported that procyanidin has multiple anticancer effects, notably for being toxic to cancer cells, on cancers such as cutaneous carcinoma, oral carcinoma, breast carcinoma, bronchogenic carcinoma, liver carcinoma, prostate carcinoma, pancreatic carcinoma, gastric carcinoma, and more, along with growth promoting effects on normal cells.

Commonly referred to as OPC in scientific circles, procyanidin is expert at treating vascular diseases because it actually increases the structural strength of weakened blood vessels, maintaining their permeability and elasticity. This occurs because OPCs help neutralize the underlying chemical cause (oxidation of living cells by free radicals) that promotes many diseases.

OPC is one of the most potent antioxidants known — 50 times more powerful than vitamin E and 20 times more so than vitamin C, according to some tests.

Grape seeds and pine bark are two of the richest known sources of OPCs. Procyanidins have also been identified as abundant in walnuts husks, cranberries, certain apple varieties, pomegranates, horse chestnuts, hazelnut leaves, hawthorn, rhubarb and barley (also beer made from barley). However tests have shown that significant variation in procyanidin content can exist within these foods.

Toxicity

In 2002 a safety evaluation of OPC rich grape seed extract was undertaken to determine the toxicology of proanthocyanidins, especially in oral administration when used in various foods. The grape seed extract (GSE) was examined for acute and sub chronic oral toxicity and for mutagenic potential. The tests were undertaken using mice and rats. No evidence of acute oral toxicity and no evidence of mutagenicity was found. The results of the studies indicate a lack of toxicity and support the use of proanthocyanidin-rich extract from grape seeds for various foods.

Cardiovascular Disease

Roger Corder, Professor of Experimental Therapeutics at the William Harvey Research Institute in London, identified that procyanidin in some red wine is responsible for the reduction in the risk of coronary heart disease and the lowering of overall mortality in regular, moderate consumers of red wine.

On 30 November 2006 a research article was published in Nature magazine on Procyanidins and the significant health-giving benefits of some red wines. Nature is one of the world’s preeminent science journals.

Epidemiological studies revealed that two populations in Europe have exceptional longevity. People in the Nuoro province of Sardinia and those in the department of Gers in south west France, especially men, have a significantly greater longevity than the national average. These populations do NOT consume the “Mediterranean Diet”. Corder tested wines and identified that in this region the wines are up to 10 times more procyanidin rich than the modern, sweet, soft, quaffing style red wines so commonly made today. This is the very top of the healthy red wine “pyramid”.

Corder and his team looked at these populations and their lifestyles and determined that there was something about the wines in these regions and so began a study of the components and compounds in the wines. They designed their study so they wouldn’t know which compound worked best until the end of the trial. The researchers cultured endothelial cells and then added small amounts of red wine. The team isolated and measured the biological activity of each polyphenol in red wine. In hundreds of experiments, using wines from all over the world, procyanidin proved to be the best at regulating production of endothelin-1 to achieve the most favourable levels. Procyanidins suppressed overproduction by 50 percent.

Other compounds, such as resveratrol (a non-flavanoid polyphenol) and quercetin, were found to have an irrelevant effect.

The researchers discovered that red wines from those two regions are particularly high in procyanidins. This is because a large proportion of the grapes used to produce the local wines in these regions are the flavanoid-rich Tannat. Furthermore the traditional wine-making techniques in the south west of France, where the grape skins and seeds remain in contact with the juice for an extended period during fermentation and maceration, significantly increased the concentration of procyanidins in the red wines.

The groundbreaking research by Professor Roger Corder and colleagues established that:

1. Procyanidins lower blood pressure by suppressing endothelin-1,

a peptide that has an undesirable vasoconstriction effects. They also increase nitric oxide in the blood causing vasodilation and increased blood flow

2. Procyanidins decrease platelet aggregation,

thus preventing clot formation and blockage of arteries

3. Procyanidins prevent oxidation of LDL-cholesterol.

High blood cholesterol levels are a major risk factor for heart disease because LDL-cholesterol can accumulate in the artery wall where after oxidation it causes inflammation and the formation of plaque. When LDL-cholesterol is protected from oxidation it is less likely to cause atherosclerosis

4. Very few wines have exceptionally high concentrations of procyanidins.

Corder tested many wines and identified only a few regions of the world that consistently have the highest concentrations of procyanidins

Powerful Antioxidants

OPCs have a deservedly high reputation as antioxidants that quench free radicals and potentiate other antioxidants. In one in vitro study OPCs prolonged the life span of vitamin C by 400 percent. Another in vitro study showed that exposing blood vessel linings to pine bark OPCs boosted their vitamin E content by 15 percent. Grape seed has also shown recycling and potentiating effects. The test tube-based activity of vitamin E, in a system mimicking cell membranes, has shown enhancement by grape seed OPCs.

A mouse study, at the Creighton University School of Pharmacy in Omaha, Neb., found that a patented grape seed extract protected tissue from oxidation better than the antioxidant vitamins C and E or beta-carotene.

Grape seed OPCs were observed to be a stronger antioxidant than vitamins C and E, even when the two vitamins were combined, in an in vitro experiment testing the response of human mouth cells to the free radical damage caused by smokeless tobacco.

Preventing Atherosclerosis

The role of oxidation in the development of hardened arteries (atherogenesis) is increasingly understood. Oxidized LDL (low-density lipoproteins) cholesterol provokes numerous adverse responses including inflammation, smooth muscle cell proliferation and clotting mechanisms to the cells that line blood vessel walls. All this leads to atherosclerosis.

A grape seed extract with 50 percent OPCs and 50 percent phenolic acids prevented such oxidation of pig LDL in vitro. OPCs may also prevent atherosclerosis in other ways. For example, two in vitro studies found that a patented pine bark extract modulated the release of nitric oxide, which affected the dilation diameter of blood vessels.

Similarly this is one of Corder’s primary finding — that high blood cholesterol levels are a major risk factor for heart disease and stroke because LDL-cholesterol can accumulate in the artery wall where after oxidation it causes inflammation and the formation of plaque. When LDL-cholesterol is protected from oxidation it is less likely to cause atherosclerosis.

Researchers compared the effects of patented pine bark extract OPCs with aspirin on smoking-induced platelet aggregation in three groups of smokers. They found that platelet aggregation was inhibited by both 500 mg aspirin and 100-125 mg pine bark extract. Because of the increased bleeding time caused by aspirin, the authors conclude that pine bark offers an “advantageous risk-benefit ratio.”

Increasingly, studies are raising questions of safety with long term use of aspirin by the “worried well” to prevent heart attach. Studies have found sustained use almost doubles the risk of admittance to hospital due to internal bleeding.

OPCs appear to inhibit several factors contributing to atherosclerosis, but do they actually prevent the condition? Yes, is the conclusion according to recent animal experiments. Researchers at a soy sauce manufacturing plant in Noda City, Japan, fed rabbits a diet that caused high blood cholesterol and severe atherosclerosis in the control animals. Their blood levels of peroxides (a measure of oxidation) increased by 10 times. Another group of rabbits ate the same diet but supplemented with grape seed OPC extract amounting to either 0.1 or 1 percent of their diet. The supplemented rabbits also developed high cholesterol levels; however, they had no detectable peroxides in their blood. Even more impressive, their blood vessels had no atherosclerosis whatsoever. These findings have been confirmed by other research on grape seed and pine bark OPCs. This emphasizes that the issue is the degree of oxidation of the cholesterol and not high cholesterol itself per se.

Although promising data on OPCs and atherosclerosis prevention primarily come from test tube and animal studies, epidemiological research may lend credence to the value of OPCs in human health. In fact, OPCs may help explain the “French Paradox,” or why low coronary heart disease rates exist in French provinces known for high-fat foods and red wine consumption. These populations do NOT have a ‘Mediterranean diet’.

The French Paradox was first proposed by Dr Serge Renaud in 1991. Dr Renaud’s attendance at the Wine & Health Symposium (headlined by Professor Corder) in Pau, France, in 2007 was confirmation he supports Corder’s research that identified procyanidins as the explanation of The French Paradox. Corder concludes from his research and epidemiological studies that OPCs are the cause of the exceptional longevity in some populations in south-west France and Sardinia. Corder proposes this is the REAL French Paradox.

Red wine could be considered an alcohol tincture of several potent flavonoids, including OPCs from grape seeds. At the University of Padova, Italy, they fed volunteers a high-fat meal with and without red wine. Post-meal plasma peroxide levels were much lower in those who drank wine.

OPCs also appear to prevent damage caused by atherosclerosis by preventing ischemic reperfusion injury. With atherosclerosis, a clot can restrict blood flow to the heart. If this clot is broken up, blood comes pouring back into the tissue. That process, paradoxically, results in an incredible amount of free radical damage. At the University of Connecticut School of Medicine in Farmington, they subjected animal hearts to blood-flow constriction and release. Compared with control animals, the animals supplemented with a patented grape seed extract had 38 percent less heart damage and 50 percent less creatine kinase release, a marker of tissue damage.

Breast Cancer

Studies have shown that the production of estrogens in breast cancer tissue plays a major role in tumor progression. In vitro studies have shown that procyanidin B dimers were able to reduce androgen-dependent tumor growth, indicating that these chemicals reduce the production of estrogens from the androgen substrates.

In a study researchers demonstrated that procyanidin B dimers in red wine could be used as chemopreventive agents against breast cancer by inhibiting the conversion of androgens to estrogens in breast tissues. The researchers estimated that a single four-ounce glass of red wine daily could provide enough procyanidin B dimer to inhibit aromatase activity in an average post-menopausal woman.

Prostate Cancer Protection

A study concluded that procyanidin can induce apoptosis (self-destruction of cancer cells) and necrosis (death of cells as a result of an outside agent) of prostate cancer PC-3 cells in a mitochondrion-dependent manner. The significant changes observed occurred to varying degrees according to dose and time dependent manners within a few hours of treatment beginning.

Prostate carcinoma (PCa) is one of the most prevalent cancers in men. The rate of PCa-related death increases every year. Until now, there has been no effective therapy that has an obvious effect on extending the life span of PCa sufferers. Other traditional therapies, such as radiotherapy, chemotherapy, and surgery, cannot prevent PCa from developing into metastatic clones and becoming androgen-refractory. Therefore, developing new therapeutic strategies targeting apoptosis induction would be of real value in controlling the proliferation as well as the invasiveness of advanced PCa.

The study aimed to determine whether procyanidin-induced apoptosis and necrosis of PC-3 cells is related to Mitochondrial membrane potential. The mitochondrion is a structure in the cytoplasm (outside the nucleus) of all cells except bacteria in which food molecules (sugars, fatty acids, and amino acids) are broken down in the presence of oxygen and converted into energy. So as the cell “powerhouse” it is vital to human health. It is also an important structure within the cells that regulates cell death. The study showed that Mitochondrial membrane potential was significantly reduced in PC-3 cells by treatment with procyanidin. Thus toxicity of procyanidin to these cancer cells was demonstrated.

Other Cancer Protection

Other in vitro studies also suggest OPCs provide cancer protection. OPCs in Vaccinium-family berries, including blueberry, lingonberry and cranberry, block tumor growth by preventing protein synthesis in tumor cells, thereby preventing them from multiplying. Also in the laboratory, barley bran OPCs transformed human myeloid leukemia cells into cells that were no longer cancerous. Another in vitro study found that a patented grape seed extract killed cancer cells; inhibited growth of human breast, lung, stomach and myelogenous leukemia cells by up to 73 percent; and enhanced normal cell growth.

Betel nut, a stimulant chewed by millions of Asians, also contains OPCs. In a small study into the inhibitory effect of betel nut extracts on endogenous nitrosation in humans, the researchers noted that OPCs may play a major role in natural cancer prevention.

Other Health Benefits

Protection again viruses may also occur with OPCs. In vitro studies with OPCs from hawthorn (Crataegus oxyacantha) killed the herpes (HSV-1) and HIV viruses.

Venous insufficiency is a common condition in which the veins and muscles, primarily in the legs, are not able to properly return blood to the heart. Walking becomes painful and difficult. Italian research has shown that grape seed extract can help. Twenty-four patients with chronic venous insufficiency were treated with 100 mg grape seed extract daily. The improvements were visible in 10 days: 70 percent of the patients had less edema and 50 percent had less pain. Bilberry and other bioflavonoids have been used for vein problems for many years in Europe. They may have a similar mechanism of action, or their active constituents may include OPCs.

The body is also protected from toxins by OPCs. Acetaminophen, the active ingredient in Tylenol, is a potent liver toxin, annually causing 75,000 cases of poisoning requiring hospitalization in the United States. Animal experiments showed that a week of pretreatment with 100 mg/kg of a patented grape seed extract prevented liver damage from acetaminophen. Organ damage was assessed by studying liver cells for damage and also by monitoring the animal’s health.

Procyanidins and Beauty

More than just disease prevention, OPCs may make us more youthful looking. Oxidation damage causes most visible signs of aging in our skin. By preventing this damage, skin will stay younger looking. One way to achieve this is to reduce the damaging effects of ultraviolet (UV) light. Sunscreen products have incorporated a variety of antioxidants with the intent that they will prevent sun injury to the skin. In one study, grape seed OPCs exerted a solo antioxidant effect at a level of potency on a par with vitamin E-protecting different polyunsaturated fatty acids from UV light-induced lipid peroxidation. In this same study, the grape OPCs synergistically interacted with vitamin E, recycling the inactivated form of the vitamin into the active form and thus acting as a virtual vitamin E extender.

Part of the aging process is the degradation of skin by the enzyme elastase, which is released with the inflammatory response. OPCs specifically block elastase, thus maintaining the integrity of elastin.

OPCs may even help us grow a thick head of hair, if the results of animal experiments apply to humans. Japanese researchers shaved mice and found that 40 percent of their hair grew back naturally. When a 1 percent solution of any of three proanthocyanidins was applied to the skin, however, between 70 and 80 percent of the hair grew back. Test tube studies confirm that OPCs actually stimulate the hair keratinocytes to produce three times more hair than the controls.

The health benefits of OPCs have prompted some researchers to suggest there should be an official recommended optimal intake. Doses used in many animal experiments are 100 mg/kg of body weight, which is equivalent to between 50 and 200 mg for the average adult, according to Bagchi. With the prevalence of refined foods today, our intake is much lower than the amount we likely evolved with, but there has been little attempt to quantify current OPC intake. However according to Corder, one glass per day of procyanidin rich red wine provides cardiovascular benefits. This has been the experience of New Zealand consumers of the wines from south west France. Those wines, which have been tested for the procyanidin content, have up to 330 mg per 125ml serving.

While there is more research to be undertaken the evidence mounts for the healthy benefits of procyanidin. The good news is that procyanidins are abundantly available in various food types without waiting for the processes of commercial certification to be completed. To emphasize – procyanidins are available in beneficial doses naturally. Unnaturally high and unproven to be safe doses are not required with procyanidin.



Source by Rob Lauder

What Is Ransomware?

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For several years now, ransomware attacks have been steadily increasing. Back in 2013, CryptoLocker hit the headlines as one of the first ransomware programs to be released. Until 2014, when its distribution networks were taken down, CryptoLocker wreaked havoc infecting countless personal and business computers. Since then, there have been many new ransomware infections, some of which use the CryptoLocker name, but are in fact different programs. In this post, we explain what ransomware is, the effect that it can have on your business and what you can do to protect yourself against the threat.

Ransomware is a form of malware. Malware is a general term for malicious software programs, commonly referred to as viruses, which are designed to enter our computers and other devices without our knowledge or permission, and with the intention of causing harm to our devices and the data that lives on them. There are many different types of malware and each has a different effect. Some, for example, may have been designed with the intention to compromise our data, whilst others will simply cause damage to our devices.

Ransomware is a form of malware that has the capacity to encrypt your files, without your knowledge, before demanding payment for their return. Very often, there is also a time limit imposed for the payment. It’s important to note that there’s no guarantee that your files will be decrypted once payment has been made.

As well as targeting files containing valuable personal or business data such as photos, spreadsheets and documents, ransomware programs can also have the ability to lock down system files as well, which could render applications, web browsers and even entire operating systems unusable. Although the original CryptoLocker infection targeted Windows, the current threat is not limited to PCs. Macs and mobile devices with the Android operating system installed are also at risk of ransomware infections.

The most common way that ransomware is spread is via infected Email attachments and links contained within Emails. Once an infected file has been opened, it is able to infect your system. It can be difficult to detect files that are infected as the malware is often concealed. The file extension may be changed and the malicious code is compressed into a zip file. Infection can also occur though installation of applications from untrusted or unknown publishers, as these may also contain ransomware. Once it has infected your system, ransomware works quietly in the background and connects to a remote server to encrypt files.

Once the ransomware has encrypted your files, you will receive a pop-up message demanding payment. The amount of money that is demanded using ransomware programs varies substantially, ranging from a few hundred to several thousands of pounds. It is common for payment to have to be made in an anonymous currency, such as Bitcoin. As previously mentioned, there is no guarantee that your files will be decrypted if you pay the ransom.

As you can probably imagine, ransomware can have very serious consequences for businesses. If you hold sensitive internal and customer information on your systems, and it is not securely backed up, you will be at risk of losing it if your systems are infected with ransomware. If your data is backed up, you will be able to recover your important files, but this goes far from solving the problem. You will still have experienced a potentially very serious data breach, which can have a number of devastating consequences of its own. It can cost companies a significant amount of money to deal with a data breach, which can also damage your reputation and lead to loss of business and potentially even legal cases being brought against your company.

Because ransomware renders files unusable, the first thing you should do is to ensure that all of your data is securely backed up. We would recommend a remote backup service, as this is arguably the safest and most efficient method of backing up your critical data. This should, however, be seen as an additional precaution, rather than a complete solution to the threat of ransomware. Prevention is always better than cure, so make sure that you have business-grade anti-virus and anti-spam software solutions installed, and that these are always kept up-to-date. Anti-spam software will help to detect any suspicious Emails and prevent them from entering your inboxes. Anti-virus software will detect malware threats and halt them before they are able to do any harm to your systems. It’s better to be safe than sorry.



Source by Della Bentham

Your coffee maker can also do these other amazing things; find out

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By: Lifestyle Desk | New Delhi |

Published: April 30, 2020 9:10:04 am





coffee maker, coffee maker hacks, other ways to use the coffee maker, indian express, indian express news Did you know about these hacks? (Source: Getty/Thinkstock)

Do you have a coffee maker at home? Chances are you may have only used to it to make coffee, as you should, because you have purchased it for the exact purpose. But did you know that there are many other interesting ways in which you can use the appliance? Wondering what they are? Read on.

Boiling eggs

Yes, it is possible! There is no need to think about any other way to boil eggs when you have a coffee maker at home. All you have to do is put the eggs in the decanter and add some water to it. When you set the timer, make sure the eggs are completely submerged. Let it sit for 10-12 minutes, then take them out and put them in cold water. Easy, right?

coffee maker, coffee maker hacks, other ways to use the coffee maker, indian express, indian express news You can utilise the basket at the top of the coffee maker to steam vegetables. (Source: Getty/Thinkstock)

Ramen preparation

Craving noodles? Now make that in the coffee machine, too. For this, you will need to put the dried noodles in the coffee pot and brew. You can also add the flavour or anything else, and then wait for a few minutes for your meal to get ready. This can be especially handy when you are at a hotel.

Steaming vegetables

Have you noticed the basket at the top of the coffee maker? Well, you can utilise it to steam vegetables like broccoli and cauliflower. Just chop the veggies you want to steam, and put them inside the basket, where ground coffee is kept. Brew to maximum amount possible, of cups of water, and then enjoy your steamed vegetable.

ALSO READ | Make kitchen time more interesting using these microwave hacks

Hot chocolate

Fill the decanter with heavy cream, almost half of it, and throw in some chocolate chips. Next, you must brew two cups of water and let it sit, while stirring it now and then. If you are trying to melt chocolate, you can do that, too, in no time using the coffee maker. Just place the chocolate on a metal cup over the heat plate.

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How Should You Start Your Day?

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The late Jack Lalanne said that we started out our days in ways we would never approve of for our pets. That is, we would never put a cigarette mixed with coffee and a sweet roll into Barney the Beagle’s dish. By extension, doing the same would be completely unthinkable in the case of Cecelia the cat. But, of course, this is what we do to ourselves.

Granted, not as many of us smoke nowadays; but supposedly twenty percent here in the United States still do. In its place, for some of us, is the Starbucks phenomenon. This is the immense cup of coffee generally sweetened by the equivalent of a heaping tablespoonful of sugar ( three times what Mary Poppins thought necessary to make the “medicine go down.”) Often times this is accompanied by pastry, meaning simple carbohydrates and a lot more sugar. The only thing good about all this is that it makes us feel energized for about forty-five minutes.

Would we treat our pets this way, even if they liked it? Absolutely not. Instead, Barney, and Cecelia would always get the best pet formulas. Furthermore, we would watch their diets to keep them from getting fat. And, that is without any recent and erudite study from Harvard or Yale, suggesting that a closely monitored diet and calorie count “may” significantly impact the lifespan of four-legged family members. We know that it “will.”.

When it comes to ourselves, we do not exert the same forethought. How can that be? Perhaps we think we are not hurting ourselves. Possibly, we believe that our minor indiscretions (like an everyday twenty-four ounce cup of coffee loaded with sugar) will never get us because of our great constitutions. At least this is how we used to talk twenty years or so ago. Nowadays, we talk in terms of genes, suggesting that because of our good ones we are able to handle treats, snacks and our morning uppers. That is even when we know they are trouble–“goodies” we would never give to our pets, to say nothing of our children.

Why else do we do what we know to be questionable at best? Possibly it is because everyone else does it. Therefore it is “normal.,” and, of course, “normal” means of “no harm to anyone,” not even us. The lines in front of Starbucks in the morning suggest that this is correct. They are long, with people waiting there for their morning fix. Presumably, our days just would not be right without our “cuppa.” After all, there is at least fifteen minutes idling there, providing “free time” to collect our thoughts and get prepared to be “up and at them.” Just rolling out of bed half asleep, sliding into the car to get to the office, could never be the same.

But not all of us do this ritual all alone. There is also the morning kick-off at the office scenario. There, we do a modified form of the same thing with others. Generally, this involves a morning recapitulation of last night’s football game or, more intelligently, of the evening news. Whatever the topic, it is accompanied by caffeine, sugar and most probably simple carbohydrates. Will this ever change? Probably not in the near future. That is because the last person who “rudely” had no opinion while munching on an apple and sipping a glass of orange juice got fired for some “glaring” infraction of corporate policy.

Possibly these types of instances have become less frequent nationwide in the last decade. After all, there are people who are now allowed to occasionally work from home, and, as mentioned earlier, far fewer people are smoking. But the other bad habits still persist, as is evidenced by the line-up of cars at the coffee shops. Moreover, those of us who are into being like this really cannot conceive of a viable alternative to such an effective send off from slumber-land. Nevertheless, must there not be a better way?

Jack Lalanne started off his day with a handful of vitamins, vegetable juice and a two hour workout. In his words, it was “the most important thing of the day.” Some of us may find those words problematic–“most important thing.” That is because we know Jack was lecturing regularly, writing, giving advice and simply being our country’s’ “Grandfather of Fitness.” How can all of that not be more important than a workout, vitamins, and light breakfast?

Jack believed that what he did to start the day determined it’s outcome. Everything else was just what came later on of it’s own accord. In other words, it came about like getting to a destination, after having gotten on the right freeway, setting the cruise control. Then his “Lexus” could figuratively drive itself.

What we do in the morning hours sets our metabolisms for the rest of the day. Starting off with proper nutrition and, exercise escalates the calorie burning processes for the hours which follow. Granted, black coffee has a similar effect, but it is not even ten percent as powerful as a mile swim, a three mile run or even a humble half hour walk around the neighborhood. These activities last in effectiveness for the whole day. That is why they are superior

Initially, even a half hour walk will be harder than sitting in the car waiting in line at Starbucks. But it is definitely better in the long run; and, it does get easier within six months (so much so that we actually start looking forward to it the night before.) This is especially so if a low fat, low carbohydrate diet and a handful of vitamins are part of it

Living like this is more in line with how we treat our pets. None of us would ever expect our four legged family members to survive on artificial stimulants, poor quality food and boredom. And, none of us would ever be content with them never going out regularly go out on the leash or chasing the frizz-bee. Therefore, how can any any of us not be doing things differently when it comes to ourselves? Because we only have two legs? That all has got to change.



Source by E. Mark Clemens

Cord Blood Banking for Potential Future Transplantation

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Despite all the planning and caution, life seems to be unpredictable at one phase or the other! And it’s mostly, when individuals are faced with a health crisis, where the ailment at hand is chronic and irreversible. Humans try to secure the health of their children and loved ones in many ways. One such way that has gained popularity owing to its growing success rate, is cord blood stem cell transplant. Today, it is considered to be a miracle cure for diseases that previously doctors considered as dead-end.

The use of UCB (Umbilical Cord Blood) as a rich source for cord blood stem cells have expanded in the past decade. Today, it is already a successful practice for treating children who are suffering from haematological malignancies. Furthermore, there’s also the use of double UCB and minimized-intensity transplantation platforms that have also played its part in this expansion. In the recent times, the registry-based evaluation and the end-to-end multi-center and single institution clinical trials are researching on ways to make the UCB transplantation more acceptable. The objective is to address the complex ailments such as sickle cell disease and Kostmann’s syndrome and treat it successfully through the transplant without any side effects.

Once a baby is born, the cord blood gets collected from the placenta and the umbilical cord. The collection process is very simple and poses no risk either to the baby or the mother. These cord blood cells comprise of Haematopoietic stem cells (HSCs), which are the rare cells usually spotted in bone marrow as well.

It is said that the Haematopoietic stem cells has the capacity to produce all kinds of cells in blood i.e. white cells, red cells and platelets. They are accountable for retaining blood production all through the life. And they have also been utilized for several years in the bone marrow transplants for treating blood related ailments. In addition to that there also have been numerous reports that suggest that cord blood might also comprise of specific kind of stem cells that can create a distinctive cell that doesn’t belong to blood, for instance nerve cells. Such ideas and theories are debatable and are being researched upon for correct validation.

In the recent times, over 6000 patients globally have been treated with stem cell transplants. The U.S Food and Drug Administration still consider this process experimental and urge that there’s scope for expertise in future. However, the doctors usually procure cord blood from children whose parents have decided to store the cord blood. At the time of transplant if the patient and donor have genetic similarity then the patient’s body will accept the transfusion.

According to Mary Laughlin, Cord Blood Transplantation Expert, Case Western Reserve University, Cleveland, Ohio there’s a constant battle or action to reaction that goes on between the recipient and donor cells, and every patient and doctor wants the donor cells to win invariably. Usually, the stem cell transplants are considered more forgiving that other processes, such as the bone marrow transplants even if the donor isn’t an exact match.

As there is growth in the volunteer stem cell donor bands, the patients who are in need of it are closer to getting the best match and thus the chances of recovery is more. According to the Center for Cord Blood in Minneapolis, Minnesota, which is biggest public cord blood donor bank in United States, the chances of procuring a perfect or near perfect match today has increased exponentially in the last 4 years.

So, from Beta Thalassamia Major, Inherited Red Cell Abnormalities, Pure Red Cell Aplasia, Multiple Myeloma to Plasma Cell Leukaemia cord blood stem cell transplant has successfully treated it all. And its future is a promising one where medical experts are researching on treating other chronic ailments with UCB.



Source by Richa Verma

Exercise Science, Physics and Yin & Yang

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Greetings,

I am just sharing some insights and information regarding Exercise science,physics and Yin and Yang principles. The information is based on my background and interest in eastern and western health/wellnes systems. My experience is over ten years of strength & conditioning training with discliplines in bodybuilding, interval training, sports performance, tai chi chuan, yoga, pilates, nutrition and meditation.

There are many roads that one can choose to meet their fitness goals..this is the path i have chosen.. We can learn from Tai Chi masters all the way to trailblazers in the fitness world.

This is an ongong project … Currently the exercise menu ranges from Yoga Tree Pose->Medicine Ball Circles->Single Leg Deadlifts

Here are some excerpts: Not all in order…

Maximum Boost Workout Book © vol.1

A Seamless integration of Western exercise science and Eastern holistic arts.

(4) HIIT Workouts–High Intensity Interval Training.

‘Exercise science, physics and Yin and Yang Principles :

MBW’s philosophy works side by side with exercise science, physics and Yin & Yang principles.

Fitness Foundry workouts stimulate muscular hypertrophy (muscle growth and increase neural drive to the muscle fibers. The exercises assist in reprogramming the brain -nerves-muscle connection- in activating muscles automatically.

A chain is only as strong as its weakest link

Yin/Yang 3 principles compared with exercise science:

A) The Root of Complementary: synergist/assistor muscles- stabilization, mobility.

B) The Root of Opposites: flexion-extension/sagittal/frontal- stretch/strengthen

C) The Root of Balance: Transverse Plane-Rotary exercises/core development

Synergy of these systems is sublime and evolves with practice.

All of the dynamic motion in Maximum Boost Workout standing exercises should be rooted in the feet, released through the legs, controlled by the waist and directed through the arms and fingers (from Tai Chi Classics).

Since these exercises require total alignment, our mind body connection will improve. Lastly, moving with a slow tempo requires even more control, concentration and breathing. This allows Neuromuscular Activation, injury prevention and self-efficacy.

‘Rationale for focusing on core musculature, single leg stance and transverse/rotary exercises:’

Muscle insertion is a contributing factor to core/trunk strength, stability and development. Example: Lower back and gluteus, lower abdominals and hip flexor muscles, oblique and adductors. This is called the functional line, performing MBW is designed to around the functional line.

Lower back and abdominal muscles provides strength and stability in body movements in all planes and angles. Also is the center for all transference of power from lower body to upper body and the opposite. (Important for sports, dancing and daily activities).

MBW places the body in an unbalanced position which requires stabilization strength and coordination through out the functional line..

The human body is designed to move in all planes.

Technology has devolved us to a 2 dimensional world.

Focal Points–

Instruction on how use Heart Rate Monitor for H.I.I.T-High Intensity Interval Training

Learning New Exercises that incorporates both East & West systems

That’s all. Thank you for your time.



Source by Julio Salado